Von+Huppel+Lindau+Syndrome

Description: Von Hippel Lindau Syndrome (VHL) is an inherited multi-system disorder charcaterized by abnormal growth of the blood vessels. In the human body, normal blood vessels grow much like trees. But for a person who has VHL, they can sometimes suffer knots of the blood capillaries (angiomas/hemangioblastomas). Growths may develop in the retina, spinal cords, adrenal glands, or other parts of the body. The gene is inherited on chromosome 3 through a dominant fashion. The gene is a tumor suppressor (its role in a normal cell is to stop uncontrolled growth and proliferation).

Chromosome location: Von Hippel Lindau Syndrome is located on chromosome 3.

Treatment: Some treatments for VHL are various therapies and antiangiogenic drugs( a substance that reduces the growth of new blood vessels needed by tumors to grow).

Life Expectancy: The Life Expectancy is about 50 years.

Support Organizations: Some organizations are the DailyStrength, Family Village, and the Von Hippel-Lindau Syndrome Support Group.



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